Anticardiolipin antibody.

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Anticardiolipin antibody, recurrent thrombosis, and warfarin withdrawal.

Antibodies to cardiolipin, closely related to the 'lupus anticoagulant', are strongly implicated in the pathogenesis of thrombosis. We record six patients, all with high titres of these antibodies (greater than SD) in serum, who developed recurrent vascular occlusions six to 12 weeks after warfarin withdrawal. Five of the six had deep vein thrombosis, while the sixth suffered a myocardial infar...

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Anticardiolipin antibody in women with recurrent spontaneous miscarriage.

OBJECTIVE To determine the association between the presence of anticardiolipin antibody (ACA) and history of recurrent spontaneous miscarriage. Also, to evaluate the association between raised ACA and activated partial thromboplastin time (APTT). METHODS This is a case-control study which was carried out in Basrah Hospital for Maternity and Children, Basrah, Iraq during January to September 2...

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Study of anticardiolipin antibody in hepatitis C virus-positive patients

Several antibodies, including anticardiolipin antibodies (ACA), have been detected among chronically infected hepatitis C virus (HCV) patients. The present work aimed at ascertaining the clinical significance of ACA levels among HCV infection associated with two commonly encountered diseases, thrombocytopenia and arteriovenous-shunt malfunction. Six groups were studied, 11 HCV-positive thromboc...

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Anticardiolipin antibody-related thrombocytopenia: persistent remission after splenectomy.

The lupus anticoagulant (LAC) and anticardiolipin antibody (ACA) syndromes require particular therapeutic approaches: thrombotic accidents are an indication for oral anticoagulant therapy (OAT), whereas severe thrombocytopenia may require the special treatments used for immunologic thrombocytopenic purpura (ITP). We describe the case of a 21-year-old male who presented with axillary vein thromb...

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Anticardiolipin Antibody in Patients with Behçet's Disease with and without Vascular Thrombosis

Objective: The clinical value of IgG anticardiolipin antibody in patients with Behçet's disease with or without vascular thrombosis was evaluated.   Methods: IgG isotype of anticardiolipin (aCL) antibody was assessed in 40 Behçet's disease (BD) patients with venous or arterial thrombosis, 40 BD patients without venous or arterial thrombosis and 80 healthy subjects as controls. The levels of IgG...

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ژورنال

عنوان ژورنال: BMJ

سال: 1989

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.299.6713.1414